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12 L Supercritical CO2 Micronizer SAS

Size & Weight

The frame, the vessels and the piping are built with stainless steel, the total structure has the following characteristics:
Wide 1.9 m (6.2′), Height 2.2 cm (7.2′), Deep 1.2 cm (3.9′).
Weight 2200 kg (4850#).
Minimum room size 6×4.6 m (20’×15′), Height of 3 m (9.8′).

Vessels Volume

SAS expansion vessel volume: 12 L
Accumulator volume: 27 L

System performance

Max pressure: 200 bar
Max temperature: 85° C
Max CO2 flow: 50 kg/h
Max liquid flow: 5 kg/h

Main Characteristics

It is a production system equipped with one expansion vessel of 20 L for atomization with SAS (Supercritical Anti Solvent) process. Provided with 2 diaphragm pumps and stainless-steel frame to comply with HACCP and GMP guide lines. Voltage 460V/3ph or 400V/3ph, frequency 60Hz or 50Hz, installed Power 12 kW, Current 20 A. Computer on board and 15″ touch screen. Chiller and heater are included.


Certifications are mandatory for high pressure equipment. This machine is certified PED/CE for Europe, Africa South America and other countries accepting EU regulation or ASME/UL for North America and other countries requesting ASME regulation.
We are ISO 9001 certified by TUV, UL listed, ASME certified, CE and PED certified by Apave, CRN for Canada.

Configuration of supercritical CO2 micronizer

This machine is designed to work with two pumps, one for CO2 and another one for liquid, two expansion vessels and separated chiller and heater. It can reach max pressure (Pmax) of 200 bar and max temperature (Tmax) of 85 °C. There are two pressure set-points: the first one is for SAS vessel. There are 2 pressure gauges and voltage can be chosen on request.
It’s full automated and process is controlled by on board computer. Automation not only controls pressure and temperature but operates the full micronizzation process. 


There are two pumps, the most important is the CO2 pump, the carbon dioxide is the principal solvent and the liquid pump which is used for delivering the stating material to be atomized. At the condition of max pressure this pumps can ensure a CO2 Flow of 50 kg/h, and liquid Flow of 5 kg/h.


This system is equipped with a safety certified PLC in addition to process PLC controlling the position of the lids, the position of the valves and other safety sensors assuring safety operations. Improving safety of the operator is our mission.

Other specifications

ASME or PED certified safety valve for each vessel in isolated tubing from vessel.
PLC microprocessor Intel i7
Compressed air pressure 100 psi or 7 bar
Compressed air flow 1 CFH or 28 L/hr
2 Back pressure automatic pilot valves
2 Automatic back pressure valves

Use this production CO2 micronization system for:

Production systems are designed for small to medium volume of raw material. They are used in the pharmaceutical, food supplement and  cosmetic industry. They are compact and easy to use. Their dimensions are design to fit any kind of extraction room, ISO8 or ISO7 included. Atomization processes are included in the standard recipe list, together with the CIP cleaning recipe.

They are very flexible and can be adapted to the extraction of many different matrices simply by loading the right recipe. They are robust, designed following the Machine Directive guidelines, perfectly to work 24/7.

Gmp qualifiable

We provide all the necessary documentation requested by qualification inspectors and authority, like:

  • Material Certificate
  • Welding Certificate
  • USR (User Requirement Specifications)
  • DQ (Design Qualification)
  • IQ (Installation Qualification)
  • OQ (Operational Qualification)

Full automation

Automation is a generic term. It does not provide any information on what the machine is really doing on its own. Automation for us is not just the control of pressure, flow or temperature. We have introduced a new concept, “Adaptive Automation”, to describe a new hardware / software system capable of modifying the process cycle as required by the operator. This new automation “literally” changes the way the system will produce the extract, something completely different from simply controlling pressure and temperature.

Remote assistance

We give full support via internet to solve technical problems quickly and for routine maintenance interventions. In many cases our technicians are able to solve problems online without having to physically go to the installation site, by connecting to the system via the internet, thanks to cutting-edge tools for remote support.  If it is not technically possible to solve the problem remotely, the technician will be responsible for organizing an intervention on site. All support technicians are qualified and with years of experience.

Design on URS

By User Requirement Specifications we mean the functions that a specific device must have in order to satisfy the needs and requirements of its end user; or, more simply, it is what a device is expected to be able to offer to those who use it, in terms of functionalities. Generally their specification takes place through the drafting of a specific document (called User Requirement Specifications – URS) which takes place in the validation phase of the machinery itself, therefore before this is actually designed.